学习工作经历：

2010.09-2014.06 江南大学 高分子材料与工程 学士

2014.09-2019.09 南京大学 高分子化学与物理 博士

2019.11-至今 湖南工程学院 材料化工学院 专任教师

研究方向：

生物大分子纳米载体，功能高分子，金属药物，药物递送，响应性药物控释

项目经历：

1. 2025年湖南省芙蓉计划青年人才项目（青年托举类）

2. 国家自然科学青年基金（2021-2023）

3. 湖南省自然科学青年基金（2021-2023）

4. 湖南省教育厅优秀青年基金（2022-2024）

5. 湖南工程学院新进博士科研启动基金（2020-2022）

6. 南京大学研究生跨学科科研创新计划项目（2016-2018）

科研成果：

1. DuKe; Li Xiao*; Feng, Fude*. Polymer–Drug Conjugates Codeliver a Temozolomide Intermediate and Nitric Oxide for Enhanced Chemotherapy against Glioblastoma Multiforme, ACS Applied Bio Materials, 2024, 7(3), 1810–1819.

2. Li, Xiao; Du, Ke; Sun, Jian; Feng, Fude*. Apoferritin as a Carrier of Cu(II) Diethyldithiocarbamate and Biomedical Application for Glutathione-Responsive Combination Chemotherapy. ACS Appl. Bio Mater. 2020, 3(1): 654-663.

3. Li, Xiao; Zhang, Yajie; Chen, Hong; Sun, Jian; Feng, Fude*. Protein Nanocages for Delivery and Release of Luminescent Ruthenium(II) Polypyridyl Complexes. ACS Appl. Mater. Interfaces 2016, 8(35): 22756−22761.

4. Li, Xiao; Zhang, Yajie; Sun, Jian; Chen, Weijian; Wang, Xuewei; Shao, Fenli; Zhu, Yuyu; Feng, Fude*; Yang Sun. Protein Nanocage-Based Photo-Controlled Nitric Oxide Releasing Platform. ACS Appl. Mater. Interfaces 2017, 9(23): 19519–19524.

5. Li, Xiao; Shao, Fenli; Sun, Jian; Du, Ke; Sun, Yang; Feng, Fude*. Enhanced Copper−Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme. ACS Appl. Mater. Interfaces 2019, 11(45): 41935–41945. 

6. Zhang, Yajie; Li, Xiao; Wu, Tiantian; Sun, Jian; Wang, Xuewei; Cao, Leilei; Feng, Fude*. Cationic Polythiophenes as Gene Delivery Enhancer. ACS Appl. Mater. Interfaces 2017, 9(20): 16735−16740.

7. Sun, Jian; Li, Xiao; Du, Ke; Feng, Fude*. A Water Soluble Donor-Acceptor-Donor Conjugated Oligomer as a Photosensitizer for Mitochondria-Targeted Photodynamic Therapy. Chem. Commun. 2018, 54(66): 9194−9197.

8. Ji, Jinkai; Li, Xiao; Wu, Tiantian; Feng, Fude*. Spiropyran in Nanoassemblies as a Photosensitizer for Photoswitchable ROS Generation in Living Cells. Chem. Sci. 2018, 9(26): 5816−5821.

9. Sun, Jian; Li, Xiao; Cao, Jia; Sun, Qi; Zhang, Yajie; Wang, Xuewei; Wu, Tiantian; Hu, Xiantao; Feng, Fude*. Mitochondria Targeting Fluorescent Probes Based on Through Bond Energy Transfer for Mutually Imaging Signaling Molecules H₂S and H₂O₂. Chem. - Eur. J. 2019, 25(39): 9164−9169.

10. Cao, Leilei; Li, Xiao; Wu, Tiantian; Cai, Xuetong; Zhang, Yajie; Ji, Jinkai; Zhang, Xiaoran; Gao, Yajing; Fude Feng*. Facile Synthesis of a Carnosine-Pendent Cationic Polymer via Free Radical Polymerization and Application in Gene Delivery, Macromol. Chem. Phys. 2019, 220(15), 1900049.

11. Chen, Weijian; Zhang, Yajie; Li, Xiao; Chen, Hong; Sun, Jian; Feng, Fude*. H₂S Activated Drug Release from Protein Cages. ACS Appl. Mater. Interfaces 2017, 9(39): 33571−33575.

12. Chen, Weijian; Li, Shuyi; Li, Xiao; Zhang, Chi; Hu, Xiantao; Zhu, Fan; Shen, Guosong; Feng, Fude*. Iron Sulfur Clusters in Protein Nanocages for Photocatalytic Hydrogen Generation in Acidic Aqueous Solutions. Chem. Sci. 2019, 10(7): 2179−2185.

13. Chen, Weijian; Cai, Xuetong; Ji, Luyang; Li, Xiao; Wang, Xuewei; Zhang, Xiaoran; Gao, Yajing; Feng, Fude*. A Photosynthesis-Inspired Supramolecular System: Caging Photosensitizer and Photocatalyst in Apoferritin. Photosynth. Res. 2019, 142(2): 169−180.

14. 光响应二乙基二硫代氨基甲酸酯前体分子及其制备方法和应用，ZL202210320348.3.

15. 一种光/pH双重响应偶联药物前体化合物及其制备方法和应用，ZL202210415670.4.

16. 光/酶双重响应药物前体化合物及其制备方法和应用，ZL202211623250.1.

17. 获授权发明专利，一种药物前体化合物及其制备方法和应用，ZL202211622914.2.